Other and unspecified psoriasis

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L40.8, L40.9
Hospital discharge: ICD-9 6968X
Hospital discharge: ICD-8 69619
Cause of death: ICD-10 L40.8, L40.9
Cause of death: ICD-9 6968X
Cause of death: ICD-8 69619

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_PSORI_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 955 469 486
Unadjusted prevalence (%) 0.37 0.32 0.43
Mean age at first event (years) 45.00 43.50 46.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.66 [1.63, 4.34] 8.8e-5 122
15 years 0.02 3.15 [2.08, 4.77] 5.9e-8 97
5 years 0.01 5.25 [3.48, 7.93] 3.4e-15 40
1 year - - - -

Correlations

Index endpoint: L12_PSORI_NAS – Other and unspecified psoriasis
GWS hits: 3

Survival analyses between endpoints

Plot

before Other and unspecified psoriasis
after Other and unspecified psoriasis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified psoriasis