Other and unspecified psoriasis

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L40.8, L40.9
Hospital discharge: ICD-9 6968X
Hospital discharge: ICD-8 69619
Cause of death: ICD-10 L40.8, L40.9
Cause of death: ICD-9 6968X
Cause of death: ICD-8 69619

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_PSORI_NAS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 955 469 486
Unadjusted prevalence (%) 0.37 0.32 0.43
Mean age at first event (years) 45.00 43.50 46.46

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.66 [1.63, 4.34] 8.8e-5 122
15 years 0.02 3.15 [2.08, 4.77] 5.9e-8 97
5 years 0.01 5.25 [3.48, 7.93] 3.4e-15 40
1 year - - - -

Correlations

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Index endpoint: L12_PSORI_NAS – Other and unspecified psoriasis
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other and unspecified psoriasis
after Other and unspecified psoriasis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified psoriasis

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