Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
ILD_ENDPOINTS
Extra metadata
First used in FinnGen datafreeze
DF2
Interstitial lung disease endpoints
interstitial lung disease: A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
ILD_ENDPOINTS
Similar endpoints
↥List of similar endpoints to
Interstitial lung disease endpoints
based on the number of shared cases.
Broader endpoints:
None
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 27356 | 16289 | 11067 |
| Unadjusted prevalence (%) | 10.52 | 11.08 | 9.79 |
| Mean age at first event (years) | 47.13 | 45.61 | 49.37 |
Mortality
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.03 | 2.41 [2.15, 2.70] | 5.8e-52 | 2781 |
| 15 years | 0.02 | 2.86 [2.60, 3.15] | <1e-100 | 2266 |
| 5 years | 0.01 | 4.69 [4.24, 5.20] | <1e-100 | 1032 |
| 1 year | 0.00 | 8.55 [7.31, 10.00] | <1e-100 | 367 |
Correlations
↥
Index endpoint: ILD_ENDPOINTS – Interstitial lung disease endpoints
GWS hits: 27
Survival analyses between endpoints
↥Plot
before Interstitial lung disease endpoints
after Interstitial lung disease endpoints
Loading survival analyses plot
Table
Loading survival analyses table