Psoriasis vulgaris

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 L40.0
Hospital discharge: ICD-9 6961A
Cause of death: ICD-10 L40.0
Cause of death: ICD-9 6961A
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 L40.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_PSORI_VULG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40
Name in latin Psoriasis vulgaris

Summary Statistics

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Key figures

All Female Male
Number of individuals 3508 1666 1842
Unadjusted prevalence (%) 1.35 1.13 1.63
Mean age at first event (years) 50.01 48.76 51.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.13 [2.15, 4.57] 3.0e-9 289
15 years 0.02 3.72 [2.68, 5.16] 3.1e-15 240
5 years 0.01 4.90 [3.54, 6.78] 7.2e-22 88
1 year 0.00 4.16 [2.33, 7.42] 1.4e-6 14

Correlations

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Index endpoint: L12_PSORI_VULG – Psoriasis vulgaris
GWS hits: 18

Survival analyses between endpoints

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Plot

before Psoriasis vulgaris
after Psoriasis vulgaris

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psoriasis vulgaris

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