Psoriasis vulgaris

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 L40.0
Hospital discharge: ICD-9 6961A
Cause of death: ICD-10 L40.0
Cause of death: ICD-9 6961A
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 L40.0

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector L12_PSORI_VULG

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40
Name in latin Psoriasis vulgaris

Summary Statistics

Key figures

All Female Male
Number of individuals 3508 1666 1842
Unadjusted prevalence (%) 1.35 1.13 1.63
Mean age at first event (years) 50.01 48.76 51.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.13 [2.15, 4.57] 3.0e-9 289
15 years 0.02 3.72 [2.68, 5.16] 3.1e-15 240
5 years 0.01 4.90 [3.54, 6.78] 7.2e-22 88
1 year 0.00 4.16 [2.33, 7.42] 1.4e-6 14

Correlations

Index endpoint: L12_PSORI_VULG – Psoriasis vulgaris
GWS hits: 18

Survival analyses between endpoints

Plot

before Psoriasis vulgaris
after Psoriasis vulgaris

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psoriasis vulgaris