Other intervertebral disc disorders

DOID EFO MESH SNOMED PheWeb

lumbar disc degeneration: Any disease of a degenerative nature that affects the intervertebral disc.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M51

Hospital discharge: ICD-9 722

Hospital discharge: ICD-8 725

Hospital discharge: excluded ICD-9 7220|7224|7227|7228A

Hospital discharge: excluded ICD-8 7250

Cause of death: ICD-10 M51

Cause of death: ICD-9 722

Cause of death: ICD-8 725

Cause of death: excluded ICD-9 7220|7224|7227|7228A

Cause of death: excluded ICD-8 7250

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

M13_INTERVERTEB

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M50-M54

Name in latin Aliae morbositates discorum intervertebralium

Similar endpoints

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List of similar endpoints to Other intervertebral disc disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24235	13683	10552
Unadjusted prevalence (%)	9.32	9.31	9.33
Mean age at first event (years)	49.52	49.27	49.84

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.03 [0.87, 1.23]	6.9e-1	1533
15 years	0.01	1.21 [1.05, 1.41]	1.1e-2	1103
5 years	0.00	1.71 [1.46, 2.01]	4.7e-11	324
1 year	0.00	1.68 [1.25, 2.27]	6.4e-4	56

Correlations

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Index endpoint: M13_INTERVERTEB – Other intervertebral disc disorders
GWS hits: 10

Survival analyses between endpoints

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Plot

before Other intervertebral disc disorders
after Other intervertebral disc disorders

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Table

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Drugs most likely to be purchased after Other intervertebral disc disorders

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