Disorders of muscles

myositis: An inflammatory disease involving a pathogenic inflammatory response in the muscle tissue.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M60-M63
Cause of death: ICD-10 M60-M63

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_MUSCLE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Disorders of muscles based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 1803 954 849
Unadjusted prevalence (%) 0.69 0.65 0.75
Mean age at first event (years) 48.38 47.68 49.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.96 [1.88, 4.64] 2.5e-6 166
15 years 0.03 3.65 [2.44, 5.48] 3.7e-10 142
5 years 0.01 6.17 [4.11, 9.27] 1.7e-18 76
1 year - - - -

Correlations

Index endpoint: M13_MUSCLE – Disorders of muscles
GWS hits: 0

Survival analyses between endpoints

Plot

before Disorders of muscles
after Disorders of muscles

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Drugs most likely to be purchased after Disorders of muscles