Polyarteritis nodosa

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M30.0
Hospital discharge: ICD-9 4460A
Hospital discharge: ICD-8 4460
Cause of death: ICD-10 M30.0
Cause of death: ICD-9 4460A
Cause of death: ICD-8 4460

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_POLNODOSA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30
Name in latin Polyarteritis nodosa

Summary Statistics

Key figures

All Female Male
Number of individuals 106 57 49
Unadjusted prevalence (%) 0.04 0.04 0.04
Mean age at first event (years) 53.41 51.98 55.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: M13_POLNODOSA – Polyarteritis nodosa
GWS hits: 0

Survival analyses between endpoints

Plot

before Polyarteritis nodosa
after Polyarteritis nodosa

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Drugs most likely to be purchased after Polyarteritis nodosa