Polyarteritis nodosa and related conditions

Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M30
Cause of death: ICD-10 M30

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_POLYARTERETAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M30-M36
Name in latin Polyarteritis nodosa et condiciones cognatae

Similar endpoints

List of similar endpoints to Polyarteritis nodosa and related conditions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 222 133 89
Unadjusted prevalence (%) 0.09 0.09 0.08
Mean age at first event (years) 48.26 46.67 50.63

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.67 [0.32, 8.66] 5.4e-1 34
15 years 0.02 2.70 [0.65, 11.29] 1.7e-1 30
5 years 0.01 7.96 [2.75, 23.09] 1.3e-4 21
1 year - - - -

Correlations

Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits:

Survival analyses between endpoints

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before Polyarteritis nodosa and related conditions
after Polyarteritis nodosa and related conditions

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Drugs most likely to be purchased after Polyarteritis nodosa and related conditions