Klinefelter's syndrome: A sex chromosome disorder caused by the presence of an extra X chromosome in the male karyotype. Affected individuals are infertile and have a small penis and testes. They tend to have tall stature and long legs and may have difficulties with speech and language development. Gynecomastia may be present.
Filter registries Inpat., Oupat., Death
Check pre-conditions None
Include endpoints
Check conditions None
Apply sex-specific rule None
Q17_CHROMOSOMAL_ABNORMALITI_NOT_ELSEW_CLASSIFIED
Extra metadata
List of similar endpoints to
Chromosomal abnormalities, not elsewhere classified
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 261 | 143 | 118 |
| Unadjusted prevalence (%) | 0.10 | 0.10 | 0.10 |
| Mean age at first event (years) | 27.13 | 29.12 | 24.72 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.22 | 17.22 [7.20, 41.22] | 1.6e-10 | 16 |
| 15 years | 0.14 | 22.65 [9.33, 55.01] | 5.5e-12 | 14 |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Index endpoint: Q17_CHROMOSOMAL_ABNORMALITI_NOT_ELSEW_CLASSIFIED – Chromosomal abnormalities, not elsewhere classified
GWS hits: 0
before Chromosomal abnormalities, not elsewhere classified
after Chromosomal abnormalities, not elsewhere classified
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