Wet age-related macular degeneration

age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H35.31

Hospital discharge: ICD-9 3625B

Cause of death: ICD-10 H35.31

Cause of death: ICD-9 3625B

Check pre-conditions

Pre-conditions EVENT_AGE>=50

Include endpoints None

Check conditions

not WET_AMD_EARLY

Apply sex-specific rule None

WET_AMD

Extra metadata

Level in the ICD hierarchy 5

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H35

Name in latin Degeneratio maculae senilis exsudativa

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List of similar endpoints to Wet age-related macular degeneration based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.47 [1.72, 3.56]	1.1e-6	483
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

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Index endpoint: WET_AMD – Wet age-related macular degeneration
GWS hits: 7

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before Wet age-related macular degeneration
after Wet age-related macular degeneration

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