Degeneration of macula and posterior pole

DOID MESH PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#

Hospital discharge: ICD-9 3625

Hospital discharge: ICD-8 37710

Cause of death: ICD-10 H35.30, H35.31, H35.36#, H35.37#, H35.38#, H35.39#

Cause of death: ICD-9 3625

Cause of death: ICD-8 37710

Check pre-conditions None

Include endpoints

DRY_AMD

WET_AMD

MACULAR_CYST

MACULAR_HOLE

MACULAR_PUCKER

MACULA_NAS

Check conditions None

Apply sex-specific rule None

H7_MACULADEGEN

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Degeneration of macula and posterior pole based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7993	4337	3656
Unadjusted prevalence (%)	3.07	2.95	3.23
Mean age at first event (years)	70.53	70.36	70.74

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.28 [1.91, 2.72]	4.4e-20	1239
15 years	0.02	2.41 [2.04, 2.84]	2.6e-25	1178
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: H7_MACULADEGEN – Degeneration of macula and posterior pole
GWS hits: 5

Survival analyses between endpoints

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Plot

before Degeneration of macula and posterior pole
after Degeneration of macula and posterior pole

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Table

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Drugs most likely to be purchased after Degeneration of macula and posterior pole

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