Hypereosinophilic syndrome: The hypereosinophilic syndrome (HES) is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable cause, with involvement of either the heart, nervous system, or bone marrow. HES is a diagnosis of exclusion, after clonal eosinophilia (such as leukemia) and reactive eosinophilia (in response to infection, autoimmune disease, atopy, hypoadrenalism, tropical eosinophilia, or cancer) have been ruled out.
Check pre-conditions None
Check conditions None
Apply sex-specific rule None
D3_OTHERWHITECELL
Extra metadata
List of similar endpoints to
Other disorders of white blood cells
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 820 | 433 | 387 |
| Unadjusted prevalence (%) | 0.32 | 0.29 | 0.34 |
| Mean age at first event (years) | 53.86 | 50.71 | 57.38 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.60 [2.11, 6.17] | 2.9e-6 | 105 |
| 15 years | 0.03 | 4.30 [2.67, 6.95] | 2.4e-9 | 94 |
| 5 years | 0.01 | 8.03 [5.01, 12.88] | 5.3e-18 | 57 |
| 1 year | - | - | - | - |
Index endpoint: D3_OTHERWHITECELL – Other disorders of white blood cells
GWS hits: 1
before Other disorders of white blood cells
after Other disorders of white blood cells
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