Non-rheumatic valve diseases

heart valve disease: A disease involving the cardial valve.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I34, I35, I36, I37

Hospital discharge: ICD-9 424

Hospital discharge: ICD-8 39[4-6]|424

Hospital discharge: excluded ICD-8 4249|3940|3950|3960|3970

Cause of death: ICD-10 I34, I35, I36, I37

Cause of death: ICD-9 424

Cause of death: ICD-8 39[4-6]|424

Cause of death: excluded ICD-8 4249|3940|3950|3960|3970

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

I9_NONRHEVALV

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

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List of similar endpoints to Non-rheumatic valve diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.59 [3.02, 4.26]	2.8e-48	2472
15 years	0.03	4.08 [3.55, 4.70]	7.7e-85	2317
5 years	-	-	-	-
1 year	-	-	-	-

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Index endpoint: I9_NONRHEVALV – Non-rheumatic valve diseases
GWS hits: 2

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before Non-rheumatic valve diseases
after Non-rheumatic valve diseases

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