Endpoint definition
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rheumatic fever: Rheumatic fever (RF) is a multisystem inflammatory disease occurring as a post-infectious, nonsuppurative sequela of untreated streptococcus pyogenes (Group A streptococcus [GAS]) pharyngitis, and mainly occurs in individuals aged 5 to 15 years. The most common presenting signs are fever, migratory polyarthritis and carditis.
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List of similar endpoints to
Rheumatic fever incl heart disease
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 682 | 327 | 355 |
| Unadjusted prevalence (%) | 0.26 | 0.22 | 0.31 |
| Mean age at first event (years) | 48.50 | 47.17 | 49.73 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.05 | 3.33 [2.24, 4.96] | 2.8e-9 | 218 |
| 15 years | 0.03 | 3.84 [2.82, 5.21] | 9.1e-18 | 175 |
| 5 years | - | - | - | - |
| 1 year | - | - | - | - |
Index endpoint: I9_RHEUFEV – Rheumatic fever incl heart disease
GWS hits: 1
before Rheumatic fever incl heart disease
after Rheumatic fever incl heart disease
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