Ulcerative colitis (strict) with PSC

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

diagram bullet diagram downward connector

Check conditions

K11_CHOLANGI_STRICT
and K11_UC_STRICT

Apply sex-specific rule None

diagram downward connector K11_UC_STRICT_PSC

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

Key figures

All Female Male
Number of individuals 143 68 75
Unadjusted prevalence (%) 0.05 0.05 0.07
Mean age at first event (years) 29.83 30.45 29.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: K11_UC_STRICT_PSC – Ulcerative colitis (strict) with PSC
GWS hits: 0

Survival analyses between endpoints

Plot

before Ulcerative colitis (strict) with PSC
after Ulcerative colitis (strict) with PSC

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ulcerative colitis (strict) with PSC