Ankylosing spondylitis, strict definition

DOID EFO MESH SNOMED PheWeb

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Endpoint definition

↥

FinnGen phenotype data

Filter registries KELA purch., KELA reimb.

KELA reimbursements: KELA codes ANY

KELA reimbursements: ICD-10 M45

Check pre-conditions None

Include endpoints None

Check conditions

M13_ANKYLOSPON_ICD10

Apply sex-specific rule None

M13_ANKYLOSPON_STRICT

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF3

Similar endpoints

↥

List of similar endpoints to Ankylosing spondylitis, strict definition based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	757	354	403
Unadjusted prevalence (%)	0.29	0.24	0.36
Mean age at first event (years)	41.88	41.03	42.62

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.78 [0.34, 1.80]	5.6e-1	10
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

↥

Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 17

Survival analyses between endpoints

↥

Plot

before Ankylosing spondylitis, strict definition
after Ankylosing spondylitis, strict definition

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Ankylosing spondylitis, strict definition

↥