Ankylosing spondylitis

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M45
Hospital discharge: ICD-9 7200
Hospital discharge: ICD-8 7124
Cause of death: ICD-10 M45
Cause of death: ICD-9 7200
Cause of death: ICD-8 7124

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_ANKYLOSPON

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M45-M49
Name in latin Spondylarthritis/spondylitis ancylopoetica

Summary Statistics

Key figures

All Female Male
Number of individuals 1846 870 976
Unadjusted prevalence (%) 0.71 0.59 0.86
Mean age at first event (years) 42.18 42.05 42.29


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.41 [0.77, 2.58] 2.7e-1 108
15 years 0.01 1.61 [0.94, 2.74] 8.1e-2 69
5 years 0.00 1.94 [1.07, 3.49] 2.8e-2 18
1 year - - - -


Index endpoint: M13_ANKYLOSPON – Ankylosing spondylitis
GWS hits: 19

Survival analyses between endpoints


before Ankylosing spondylitis
after Ankylosing spondylitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Ankylosing spondylitis