Ankylosing spondylitis, strict definition

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Endpoint definition

FinnGen phenotype data
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Filter registries KELA purch., KELA reimb.

KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 M45

Check pre-conditions None

Include endpoints None

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Check conditions


Apply sex-specific rule None

diagram downward connector M13_ANKYLOSPON_STRICT

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 757 354 403
Unadjusted prevalence (%) 0.29 0.24 0.36
Mean age at first event (years) 41.88 41.03 42.62


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.78 [0.34, 1.80] 5.6e-1 10
15 years - - - -
5 years - - - -
1 year - - - -


Index endpoint: M13_ANKYLOSPON_STRICT – Ankylosing spondylitis, strict definition
GWS hits: 17

Survival analyses between endpoints


before Ankylosing spondylitis, strict definition
after Ankylosing spondylitis, strict definition

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Drugs most likely to be purchased after Ankylosing spondylitis, strict definition