Type 1 diabetes, wide definition, subgroup 1

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

diagram bullet diagram downward connector

Include endpoints

diagram bullet diagram downward connector

Check conditions

not PANCREATITIS
and KELA_DIAB_INSUL
and INSULIN_SHORTFAST
and INSULIN_INTER_AND_LONG

Apply sex-specific rule None

diagram downward connector T1D_WIDE1

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 6272 3027 3245
Unadjusted prevalence (%) 2.41 2.06 2.87
Mean age at first event (years) 27.14 25.50 28.66

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.66 [2.01, 3.51] 5.5e-12 486
15 years 0.01 2.19 [1.71, 2.79] 4.1e-10 242
5 years 0.00 1.23 [0.79, 1.92] 3.5e-1 25
1 year - - - -

Correlations

Index endpoint: T1D_WIDE1 – Type 1 diabetes, wide definition, subgroup 1
GWS hits: 30

Survival analyses between endpoints

Plot

before Type 1 diabetes, wide definition, subgroup 1
after Type 1 diabetes, wide definition, subgroup 1

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Drugs most likely to be purchased after Type 1 diabetes, wide definition, subgroup 1