Atopic dermatitis, strict definition

atopic eczema: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 L20.0
Hospital discharge: ICD-9 6918B
Hospital discharge: ICD-8 69100
Cause of death: ICD-10 L20.0
Cause of death: ICD-9 6918B
Cause of death: ICD-8 69100

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector ATOPIC_STRICT

Extra metadata

First used in FinnGen datafreeze DF3
Parent code in ICD-10 L20
Name in latin Eczema atopicum

Summary Statistics

Key figures

All Female Male
Number of individuals 6412 4434 1978
Unadjusted prevalence (%) 2.47 3.02 1.75
Mean age at first event (years) 26.53 26.82 25.89


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.32 [0.77, 2.24] 3.1e-1 145
15 years 0.01 1.65 [1.02, 2.67] 4.1e-2 106
5 years 0.00 3.13 [1.97, 4.97] 1.4e-6 43
1 year 0.00 4.02 [1.98, 8.15] 1.1e-4 10


Index endpoint: ATOPIC_STRICT – Atopic dermatitis, strict definition
GWS hits: 25

Survival analyses between endpoints


before Atopic dermatitis, strict definition
after Atopic dermatitis, strict definition

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Drugs most likely to be purchased after Atopic dermatitis, strict definition