Crohn's disease of large intestine

Crohn's colitis: Crohn's disease affecting the colon.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K50.1
Cause of death: ICD-10 K50.1

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector CHRONLARGE

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Colitis regionalis

Summary Statistics

Key figures

All Female Male
Number of individuals 1004 573 431
Unadjusted prevalence (%) 0.39 0.39 0.38
Mean age at first event (years) 43.72 42.68 45.11

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.78 [2.12, 6.73] 6.6e-6 40
15 years 0.03 3.98 [2.18, 7.29] 7.3e-6 36
5 years 0.01 5.63 [2.82, 11.23] 9.7e-7 15
1 year - - - -

Correlations

Index endpoint: CHRONLARGE – Crohn's disease of large intestine
GWS hits: 2

Survival analyses between endpoints

Plot

before Crohn's disease of large intestine
after Crohn's disease of large intestine

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Drugs most likely to be purchased after Crohn's disease of large intestine