COPD, hospital admissions

chronic obstructive pulmonary disease: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat.

Hospital Discharge: ICD-10 J44
Hospital discharge: ICD-9 4912
Hospital discharge: ICD-8 49104

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector COPD_HOSPITAL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J40-J47
Name in latin Alii morbi obstructivi chronici pulmonum

Similar endpoints

List of similar endpoints to COPD, hospital admissions based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 8963 2752 6211
Unadjusted prevalence (%) 3.45 1.87 5.49
Mean age at first event (years) 63.75 60.30 65.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 0.34 [0.18, 0.64] 9.7e-4 3138
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: COPD_HOSPITAL – COPD, hospital admissions
GWS hits: 3

Survival analyses between endpoints

Plot

before COPD, hospital admissions
after COPD, hospital admissions

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Drugs most likely to be purchased after COPD, hospital admissions