Diabetic maculopathy

macular degeneration: Loss of vision in the central portion of the retina (macula), secondary to retinal degeneration. [ NCIT:P378 ]

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H36.01*
Cause of death: ICD-10 H36.01*

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_MACULOPATHY

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2273 931 1342
Unadjusted prevalence (%) 0.87 0.63 1.19
Mean age at first event (years) 50.75 48.86 52.06

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 5.85 [4.05, 8.46] 4.9e-21 406
15 years 0.04 6.07 [4.25, 8.67] 4.2e-23 368
5 years 0.01 8.92 [6.90, 11.54] 1.7e-62 168
1 year 0.00 7.49 [4.89, 11.45] 1.7e-20 29

Correlations

Index endpoint: DM_MACULOPATHY – Diabetic maculopathy
GWS hits: 10

Survival analyses between endpoints

Plot

before Diabetic maculopathy
after Diabetic maculopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic maculopathy