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Diabetic retinopathy

DOIDEFOMESHSNOMED PheWeb

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital discharge: ICD-9 3620
Cause of death: ICD-9 3620

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_RETINOPATHYDIAB

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 4524 2020 2504
Unadjusted prevalence (%) 1.74 1.37 2.21
Mean age at first event (years) 47.62 45.05 49.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.36 [4.05, 7.10] 8.9e-32 840
15 years 0.04 5.91 [4.69, 7.44] 1.1e-51 730
5 years 0.01 6.92 [5.55, 8.64] 1.6e-65 290
1 year 0.00 6.26 [4.48, 8.75] 8.4e-27 52

Correlations

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Index endpoint: H7_RETINOPATHYDIAB – Diabetic retinopathy
GWS hits: 13

Survival analyses between endpoints

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Plot

before Diabetic retinopathy
after Diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diabetic retinopathy

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