Other diabetic retinopathy

DOID EFO MESH SNOMED PheWeb

diabetic retinopathy: A chronic, pathological complication associated with diabetes mellitus, where retinal damages are incurred due to microaneurysms in the vasculature of the retina, progressively leading to abnormal blood vessel growth, and swelling and leaking of fluid from blood vessels, resulting in vision loss or blindness.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H36.09*, H36.09*E10.3, H36.09*E11.3

Cause of death: ICD-10 H36.09*, H36.09*E10.3, H36.09*E11.3

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

H7_RETINOPATHYDIAB_NAS

Extra metadata

Level in the ICD hierarchy 5

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diabetic retinopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1278	626	652
Unadjusted prevalence (%)	0.49	0.43	0.58
Mean age at first event (years)	44.29	41.08	47.38

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.13 [3.05, 8.61]	6.3e-10	197
15 years	0.04	6.13 [3.88, 9.69]	7.9e-15	178
5 years	0.01	7.43 [4.80, 11.51]	2.2e-19	65
1 year	0.00	9.34 [5.07, 17.21]	7.6e-13	15

Correlations

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Index endpoint: H7_RETINOPATHYDIAB_NAS – Other diabetic retinopathy
GWS hits: 9

Survival analyses between endpoints

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Plot

before Other diabetic retinopathy
after Other diabetic retinopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other diabetic retinopathy

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