Proliferative diabetic retinopathy

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death, Oper. in, Oper. out

Hospital Discharge: ICD-10 H36.03*
Hospital discharge: ICD-9 3620B
Cause of death: ICD-10 H36.03*
Cause of death: ICD-9 3620B
Operations: NOMESCO codes ^CKC10|^CKC15|^CKC12|^CKC50

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector DM_RETINA_PROLIF

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Proliferative diabetic retinopathy based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 10859 4950 5909
Unadjusted prevalence (%) 4.18 3.37 5.23
Mean age at first event (years) 53.19 50.66 55.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.48 [3.56, 5.65] 5.0e-37 2031
15 years 0.03 5.01 [4.16, 6.03] 4.5e-65 1842
5 years 0.01 7.73 [6.72, 8.89] <1e-100 958
1 year - - - -

Correlations

Index endpoint: DM_RETINA_PROLIF – Proliferative diabetic retinopathy
GWS hits: 16

Survival analyses between endpoints

Plot

before Proliferative diabetic retinopathy
after Proliferative diabetic retinopathy

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Drugs most likely to be purchased after Proliferative diabetic retinopathy