Unspecified diabetic retinopathy

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H3609|E1.7|E1.3
Hospital discharge: ICD-9 3620A|2504
Hospital discharge: ICD-8 25002
Hospital discharge: excluded ICD-10 E12.3+
Cause of death: ICD-10 H3609|E1.7|E1.3
Cause of death: ICD-9 3620A|2504
Cause of death: ICD-8 25002
Cause of death: excluded ICD-10 E12.3+

Check pre-conditions None

Include endpoints None

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Check conditions

DM_EYE_OPER

Apply sex-specific rule None

diagram downward connector DM_RETINA_NOS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2263 923 1340
Unadjusted prevalence (%) 0.87 0.63 1.19
Mean age at first event (years) 46.06 43.56 47.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.30 [2.30, 4.73] 9.9e-11 362
15 years 0.02 3.28 [2.23, 4.83] 1.8e-9 281
5 years 0.00 4.69 [3.22, 6.84] 9.6e-16 103
1 year 0.00 6.84 [4.19, 11.17] 1.6e-14 27

Correlations

Index endpoint: DM_RETINA_NOS – Unspecified diabetic retinopathy
GWS hits: 9

Survival analyses between endpoints

Plot

before Unspecified diabetic retinopathy
after Unspecified diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetic retinopathy