Proliferative diabetic retinopathy

proliferative diabetic retinopathy: Later stage of diabetic retinopathy, characterized by neovascularisation of the retina

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 H36.03*
Cause of death: ICD-10 H36.03*

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector H7_RETINOPATHYDIAB_PROLIF

Extra metadata

Level in the ICD hierarchy 5
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1737 772 965
Unadjusted prevalence (%) 0.67 0.53 0.85
Mean age at first event (years) 45.80 43.63 47.54

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 7.23 [4.79, 10.92] 5.2e-21 313
15 years 0.05 7.96 [5.38, 11.76] 2.4e-25 279
5 years 0.01 9.85 [6.68, 14.51] 6.9e-31 111
1 year 0.00 8.06 [4.54, 14.32] 1.1e-12 17

Correlations

Index endpoint: H7_RETINOPATHYDIAB_PROLIF – Proliferative diabetic retinopathy
GWS hits: 11

Survival analyses between endpoints

Plot

before Proliferative diabetic retinopathy
after Proliferative diabetic retinopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Proliferative diabetic retinopathy