Hypothyroidism, strict autoimmune

No definition available.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

diagram bullet diagram downward connector

Include endpoints

diagram bullet diagram downward connector

Check conditions

not E4_HYTHY_AI_EXCL

Apply sex-specific rule None

diagram downward connector E4_HYTHY_AI_STRICT

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

Key figures

All Female Male
Number of individuals 28684 23014 5670
Unadjusted prevalence (%) 11.03 15.66 5.01
Mean age at first event (years) 52.30 50.80 58.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.49 [1.30, 1.70] 5.4e-9 1927
15 years 0.01 1.69 [1.50, 1.90] 5.4e-18 1545
5 years 0.00 2.37 [2.09, 2.68] 8.7e-42 563
1 year 0.00 1.97 [1.54, 2.52] 6.9e-8 85

Correlations

Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 99

Survival analyses between endpoints

Plot

before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, strict autoimmune