Endpoint definition
↥
FinnGen phenotype data
Filter registries None
Check pre-conditions None
Check conditions
not E4_HYTHY_AI_EXCL
Apply sex-specific rule None
Extra metadata
First used in FinnGen datafreeze
DF5
Filter registries None
Check pre-conditions None
Check conditions
Apply sex-specific rule None
Extra metadata
List of similar endpoints to
Hypothyroidism, strict autoimmune
based on the number of shared cases.
Broader endpoints:
Narrower endpoints:
None
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 28684 | 23014 | 5670 |
| Unadjusted prevalence (%) | 11.03 | 15.66 | 5.01 |
| Mean age at first event (years) | 52.30 | 50.80 | 58.39 |
| Follow-up | Absolute risk | HR [95% CI] | p | N |
|---|---|---|---|---|
| 1998–2019 | 0.02 | 1.49 [1.30, 1.70] | 5.4e-9 | 1927 |
| 15 years | 0.01 | 1.69 [1.50, 1.90] | 5.4e-18 | 1545 |
| 5 years | 0.00 | 2.37 [2.09, 2.68] | 8.7e-42 | 563 |
| 1 year | 0.00 | 1.97 [1.54, 2.52] | 6.9e-8 | 85 |
Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 99
before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune
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