Schizoaffective disorder

DOID EFO MESH PheWeb

schizoaffective disorder: A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F25

Hospital discharge: ICD-9 2957

Hospital discharge: ICD-8 2957

Cause of death: ICD-10 F25

Cause of death: ICD-9 2957

Cause of death: ICD-8 2957

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

F5_SCHIZOAFF

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F20-F29

Name in latin Perturbationes schizoaffectivae

Similar endpoints

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List of similar endpoints to Schizoaffective disorder based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2371	1389	982
Unadjusted prevalence (%)	0.91	0.95	0.87
Mean age at first event (years)	36.78	36.92	36.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.03 [1.76, 5.21]	6.0e-5	121
15 years	0.02	3.60 [2.22, 5.85]	2.1e-7	81
5 years	0.01	5.38 [3.19, 9.07]	2.6e-10	26
1 year	-	-	-	-

Correlations

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Index endpoint: F5_SCHIZOAFF – Schizoaffective disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Schizoaffective disorder
after Schizoaffective disorder

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Table

Loading survival analyses table

Drugs most likely to be purchased after Schizoaffective disorder

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