Schizophrenia or delusion

schizophrenia: A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 F20-F29
Hospital discharge: ICD-9 295|29[7-8]
Hospital discharge: ICD-8 295|297|298[1-9]|299
Cause of death: ICD-10 F20-F29
Cause of death: ICD-9 295|29[7-8]
Cause of death: ICD-8 295|297|298[1-9]|299

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector KRA_PSY_SCHIZODEL

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 10758 5508 5250
Unadjusted prevalence (%) 4.14 3.75 4.64
Mean age at first event (years) 33.64 34.94 32.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.37 [2.73, 4.16] 8.3e-30 802
15 years 0.02 3.59 [2.96, 4.36] 2.2e-38 542
5 years 0.01 5.47 [4.53, 6.61] 2.7e-69 215
1 year 0.00 7.57 [5.61, 10.22] 7.0e-40 58

Correlations

Index endpoint: KRA_PSY_SCHIZODEL – Schizophrenia or delusion
GWS hits: 1

Survival analyses between endpoints

Plot

before Schizophrenia or delusion
after Schizophrenia or delusion

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Schizophrenia or delusion