Epilepsy

DOID EFO MESH SNOMED PheWeb

epilepsy: A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 G40

Hospital discharge: ICD-9 345

Hospital discharge: ICD-8 345

Hospital discharge: excluded ICD-9 3452|3453

Hospital discharge: excluded ICD-8 34520

Cause of death: ICD-10 G40

Cause of death: ICD-9 345

Cause of death: ICD-8 345

Cause of death: excluded ICD-9 3452|3453

Cause of death: excluded ICD-8 34520

KELA reimbursements: KELA codes 111

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

G6_EPLEPSY

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 G40-G47

Similar endpoints

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List of similar endpoints to Epilepsy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7223	3604	3619
Unadjusted prevalence (%)	2.78	2.45	3.20
Mean age at first event (years)	43.06	39.89	46.21

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.72 [3.82, 5.84]	1.3e-46	1317
15 years	0.04	5.94 [4.95, 7.12]	2.8e-82	1140
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: G6_EPLEPSY – Epilepsy
GWS hits: 0

Survival analyses between endpoints

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Plot

before Epilepsy
after Epilepsy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Epilepsy

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