Generalized epilepsy, mode (most common among epilepsy diagnosis)

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 (mode) G40.0, G40.1
Hospital discharge: ICD-9 (mode) %345[0-1]
Hospital discharge: ICD-8 (mode) %345[0-1]
Hospital discharge: excluded ICD-8 34511
Cause of death: ICD-10 (mode) G40.0, G40.1
Cause of death: ICD-9 (mode) %345[0-1]
Cause of death: ICD-8 (mode) %345[0-1]
Cause of death: excluded ICD-8 34511

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector GE_MODE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 1202 637 565
Unadjusted prevalence (%) 0.46 0.43 0.50
Mean age at first event (years) 41.65 39.51 44.07

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.14 10.59 [6.58, 17.03] 2.2e-22 200
15 years 0.08 12.39 [8.46, 18.14] 3.2e-38 182
5 years - - - -
1 year - - - -

Correlations

Index endpoint: GE_MODE – Generalized epilepsy, mode (most common among epilepsy diagnosis)
GWS hits: 0

Survival analyses between endpoints

Plot

before Generalized epilepsy, mode (most common among epilepsy diagnosis)
after Generalized epilepsy, mode (most common among epilepsy diagnosis)

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Drugs most likely to be purchased after Generalized epilepsy, mode (most common among epilepsy diagnosis)