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Generalized epilepsy

DOIDEFOMESHSNOMED PheWeb

generalised epilepsy: A chronic condition characterised by recurrent generalised seizures.

Endpoint definition

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FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 G40.0, G40.1
Hospital discharge: ICD-9 345[0-1]
Hospital discharge: ICD-8 345[0-1]
Hospital discharge: excluded ICD-8 34511
Cause of death: ICD-10 G40.0, G40.1
Cause of death: ICD-9 345[0-1]
Cause of death: ICD-8 345[0-1]
Cause of death: excluded ICD-8 34511

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector GE

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 2124 1116 1008
Unadjusted prevalence (%) 0.82 0.76 0.89
Mean age at first event (years) 41.22 38.84 43.85

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.00 [2.31, 6.92] 7.4e-7 347
15 years 0.03 4.35 [2.29, 8.27] 7.2e-6 298
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: GE – Generalized epilepsy
GWS hits: 0

Survival analyses between endpoints

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Plot

before Generalized epilepsy
after Generalized epilepsy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Generalized epilepsy

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