Hypertensive diseases

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

Filter registries None

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HYPERTENSION

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 68036 33443 34593
Unadjusted prevalence (%) 26.16 22.76 30.59
Mean age at first event (years) 56.23 56.34 56.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.92 [1.78, 2.07] 9.0e-65 10669
15 years 0.02 2.12 [1.98, 2.27] <1e-100 8079
5 years 0.00 3.41 [3.16, 3.68] <1e-100 3514
1 year 0.00 8.09 [7.11, 9.21] <1e-100 1448

Correlations

Index endpoint: I9_HYPERTENSION – Hypertensive diseases
GWS hits: 118

Survival analyses between endpoints

Plot

before Hypertensive diseases
after Hypertensive diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive diseases