Hypertension

DOID EFO MESH SNOMED PheWeb

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death, KELA purch., KELA reimb.

Hospital Discharge: ICD-10 I10-I15, I67.4

Hospital discharge: ICD-9 4019X|4029A|4029B|4039A|4040A|4059A|4059B|4372A|4059X

Hospital discharge: ICD-8 400|401|402|403|404

Cause of death: ICD-10 I10-I15, I67.4

Cause of death: ICD-9 4019X|4029A|4029B|4039A|4040A|4059A|4059B|4372A|4059X

Cause of death: ICD-8 400|401|402|403|404

KELA reimbursements: KELA codes 205

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

I9_HYPTENS

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Hypertension based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	67991	33414	34577
Unadjusted prevalence (%)	26.15	22.74	30.58
Mean age at first event (years)	56.24	56.36	56.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.09 [1.93, 2.25]	1.5e-78	10654
15 years	0.02	2.26 [2.11, 2.42]	<1e-100	8064
5 years	0.00	3.58 [3.31, 3.86]	<1e-100	3507
1 year	0.00	8.37 [7.35, 9.53]	<1e-100	1444

Correlations

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Index endpoint: I9_HYPTENS – Hypertension
GWS hits: 118

Survival analyses between endpoints

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Plot

before Hypertension
after Hypertension

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Hypertension

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