Hypertensive Renal Disease

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I12
Hospital discharge: ICD-9 4039A
Hospital discharge: ICD-8 40399
Cause of death: ICD-10 I12
Cause of death: ICD-9 4039A
Cause of death: ICD-8 40399

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HYPTENSRD

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I10-I15
Name in latin Morbus hypertensivus renalis

Summary Statistics

Key figures

All Female Male
Number of individuals 592 209 383
Unadjusted prevalence (%) 0.23 0.14 0.34
Mean age at first event (years) 58.28 56.43 59.30

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.70 [1.54, 4.75] 5.7e-4 171
15 years 0.02 3.58 [2.28, 5.60] 2.5e-8 153
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_HYPTENSRD – Hypertensive Renal Disease
GWS hits: 0

Survival analyses between endpoints

Plot

before Hypertensive Renal Disease
after Hypertensive Renal Disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive Renal Disease