Hypertensive heart and/or renal disease

nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 I11, I12, I13
Hospital discharge: ICD-9 4029A|4029B|4039A|4040A
Hospital discharge: ICD-8 40299|40399|40499
Cause of death: ICD-10 I11, I12, I13
Cause of death: ICD-9 4029A|4029B|4039A|4040A
Cause of death: ICD-8 40299|40399|40499

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector I9_HYPTENSHR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 5641 2325 3316
Unadjusted prevalence (%) 2.17 1.58 2.93
Mean age at first event (years) 65.29 67.67 63.62

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.80 [3.96, 5.81] 1.0e-57 2017
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: I9_HYPTENSHR – Hypertensive heart and/or renal disease
GWS hits: 4

Survival analyses between endpoints

Plot

before Hypertensive heart and/or renal disease
after Hypertensive heart and/or renal disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive heart and/or renal disease