Crohn disease (strict definition, all UC cases excluded)

PheWeb

No definition available.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K50

Hospital discharge: ICD-9 555

Hospital discharge: ICD-8 5630

Cause of death: ICD-10 K50

Cause of death: ICD-9 555

Cause of death: ICD-8 5630

Check pre-conditions None

Include endpoints None

Check conditions

K11_KELAIBD

and not K11_ULCER

Apply sex-specific rule None

K11_CD_NOUC

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF3

Parent code in ICD-10 K50-K52

Name in latin Morbus Crohn

Similar endpoints

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List of similar endpoints to Crohn disease (strict definition, all UC cases excluded) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	810	463	347
Unadjusted prevalence (%)	0.31	0.32	0.31
Mean age at first event (years)	40.88	40.37	41.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.56 [1.07, 6.14]	3.5e-2	19
15 years	0.02	2.77 [1.12, 6.80]	2.7e-2	15
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: K11_CD_NOUC – Crohn disease (strict definition, all UC cases excluded)
GWS hits: 3

Survival analyses between endpoints

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Plot

before Crohn disease (strict definition, all UC cases excluded)
after Crohn disease (strict definition, all UC cases excluded)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Crohn disease (strict definition, all UC cases excluded)

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