Crohn disease (strict definition, require KELA)

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 K50
Hospital discharge: ICD-9 555
Hospital discharge: ICD-8 5630
Cause of death: ICD-10 K50
Cause of death: ICD-9 555
Cause of death: ICD-8 5630

Check pre-conditions None

Include endpoints None

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Check conditions

K11_KELACROHN

Apply sex-specific rule None

diagram downward connector K11_CD_STRICT

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Summary Statistics

Key figures

All Female Male
Number of individuals 1047 611 436
Unadjusted prevalence (%) 0.40 0.42 0.39
Mean age at first event (years) 40.22 40.09 40.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.19 [1.14, 4.20] 1.9e-2 20
15 years 0.02 2.29 [1.20, 4.35] 1.2e-2 16
5 years - - - -
1 year - - - -

Correlations

Index endpoint: K11_CD_STRICT – Crohn disease (strict definition, require KELA)
GWS hits: 3

Survival analyses between endpoints

Plot

before Crohn disease (strict definition, require KELA)
after Crohn disease (strict definition, require KELA)

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Drugs most likely to be purchased after Crohn disease (strict definition, require KELA)