Alogoneurodystrophy

reflex sympathetic dystrophy: Complex regional pain syndrome type 1 (CRPS1) is a form of complex regional pain syndrome (see this term) in which the pain is disproportionate to any known inciting event and is characterized by continuous pain, allodynia, or hyperalgesia as well as edema, coloration (changes in skin blood flow), or abnormal sudomotor activity in the region of pain. Onset of CRPS1 symptoms may occur within a few days to a month after an injury or trauma to the affected limb.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M89.0
Hospital discharge: ICD-9 7337
Cause of death: ICD-10 M89.0
Cause of death: ICD-9 7337

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_ALGONEURO

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M89
Name in latin Algoneurodystrophia

Summary Statistics

Key figures

All Female Male
Number of individuals 553 418 135
Unadjusted prevalence (%) 0.21 0.28 0.12
Mean age at first event (years) 47.42 46.61 49.93

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.62 [1.38, 9.49] 8.9e-3 26
15 years 0.02 3.34 [1.22, 9.16] 1.9e-2 23
5 years 0.01 5.25 [2.17, 12.71] 2.4e-4 11
1 year - - - -

Correlations

Index endpoint: M13_ALGONEURO – Alogoneurodystrophy
GWS hits: 0

Survival analyses between endpoints

Plot

before Alogoneurodystrophy
after Alogoneurodystrophy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Alogoneurodystrophy