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Osteopathies and chondropathies

DOIDEFOMESHSNOMED PheWeb

secondary hypertrophic osteoarthropathy: Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99
Cause of death: ICD-10 M80-M94, M90.6*C40.99, M90.6*C41.99

Check pre-conditions None

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Include endpoints

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 11264 7064 4200
Unadjusted prevalence (%) 4.33 4.81 3.71
Mean age at first event (years) 51.21 53.39 47.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 3.14 [2.50, 3.95] 1.7e-22 1371
15 years 0.03 4.07 [3.41, 4.86] 6.1e-55 1228
5 years - - - -
1 year - - - -

Correlations

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Index endpoint: M13_OSTEOCHONDRO – Osteopathies and chondropathies
GWS hits: 0

Survival analyses between endpoints

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Plot

before Osteopathies and chondropathies
after Osteopathies and chondropathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Osteopathies and chondropathies

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