Paget disease

osteitis deformans: A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M88
Hospital discharge: ICD-9 7310
Hospital discharge: ICD-8 72199
Cause of death: ICD-10 M88
Cause of death: ICD-9 7310
Cause of death: ICD-8 72199

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_PAGET

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteitis deformans Paget

Summary Statistics

Key figures

All Female Male
Number of individuals 67 34 33
Unadjusted prevalence (%) 0.03 0.02 0.03
Mean age at first event (years) 61.38 60.97 61.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Correlations

Index endpoint: M13_PAGET – Paget disease
GWS hits:

Survival analyses between endpoints

Plot

before Paget disease
after Paget disease

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