Osteonecrosis

osteonecrosis: A none disease characterized by death of bone tissue due to a lack of blood supply.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M87
Hospital discharge: ICD-9 7334
Cause of death: ICD-10 M87
Cause of death: ICD-9 7334

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_OSTEONECROSIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteonecrosis

Summary Statistics

Key figures

All Female Male
Number of individuals 763 434 329
Unadjusted prevalence (%) 0.29 0.30 0.29
Mean age at first event (years) 57.09 57.48 56.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.65 [2.39, 9.07] 6.2e-6 73
15 years 0.04 6.26 [3.65, 10.75] 2.9e-11 66
5 years 0.01 11.87 [7.49, 18.83] 7.4e-26 42
1 year - - - -

Correlations

Index endpoint: M13_OSTEONECROSIS – Osteonecrosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Osteonecrosis
after Osteonecrosis

loading spinner Loading survival analyses plot