Scoliosis

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M41
Hospital discharge: ICD-9 7373
Cause of death: ICD-10 M41
Cause of death: ICD-9 7373

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_SCOLIOSIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M40-M43
Name in latin Scoliosis

Summary Statistics

Key figures

All Female Male
Number of individuals 1478 1154 324
Unadjusted prevalence (%) 0.57 0.79 0.29
Mean age at first event (years) 39.26 39.30 39.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.11 [0.97, 4.59] 6.0e-2 46
15 years 0.02 2.63 [1.24, 5.57] 1.2e-2 42
5 years 0.01 6.00 [3.36, 10.72] 1.3e-9 27
1 year - - - -

Correlations

Index endpoint: M13_SCOLIOSIS – Scoliosis
GWS hits: 0

Survival analyses between endpoints

Plot

before Scoliosis
after Scoliosis

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