Deforming dorsopathies

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

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FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M40-M43
Cause of death: ICD-10 M40-M43

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_DEFORMDORSO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Deforming dorsopathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 5765 3833 1932
Unadjusted prevalence (%) 2.22 2.61 1.71
Mean age at first event (years) 47.47 47.33 47.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.31 [1.70, 3.13] 8.3e-8 273
15 years 0.02 2.49 [1.90, 3.25] 2.3e-11 226
5 years 0.00 3.21 [2.33, 4.43] 1.2e-12 102
1 year 0.00 3.55 [2.17, 5.78] 3.9e-7 23

Correlations

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Index endpoint: M13_DEFORMDORSO – Deforming dorsopathies
GWS hits: 0

Survival analyses between endpoints

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Plot

before Deforming dorsopathies
after Deforming dorsopathies

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Drugs most likely to be purchased after Deforming dorsopathies

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