Deforming dorsopathies

scoliosis: A congenital or acquired spinal deformity characterized by lateral curvature of the spine.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M40-M43
Cause of death: ICD-10 M40-M43

Check pre-conditions None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_DEFORMDORSO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Deforming dorsopathies based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5765 3833 1932
Unadjusted prevalence (%) 2.22 2.61 1.71
Mean age at first event (years) 47.47 47.33 47.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.31 [1.70, 3.13] 8.3e-8 273
15 years 0.02 2.49 [1.90, 3.25] 2.3e-11 226
5 years 0.00 3.21 [2.33, 4.43] 1.2e-12 102
1 year 0.00 3.55 [2.17, 5.78] 3.9e-7 23

Correlations

Index endpoint: M13_DEFORMDORSO – Deforming dorsopathies
GWS hits: 0

Survival analyses between endpoints

Plot

before Deforming dorsopathies
after Deforming dorsopathies

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Deforming dorsopathies