Spondylolisthesis/Spondylolysis

spondylolisthesis: A condition in which there is forward displacement of a vertebral bone over the on below it.

Endpoint definition

FinnGen phenotype data
diagram bullet diagram downward connector

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 M43.0, M43.1
Hospital discharge: ICD-9 7384
Cause of death: ICD-10 M43.0, M43.1
Cause of death: ICD-9 7384

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule None

diagram downward connector M13_SPONDYLOLISTHESIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3335 2139 1196
Unadjusted prevalence (%) 1.28 1.46 1.06
Mean age at first event (years) 54.85 55.55 53.60

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.44 [1.60, 3.73] 3.5e-5 145
15 years 0.02 2.44 [1.58, 3.77] 6.3e-5 123
5 years 0.00 2.86 [1.85, 4.43] 2.5e-6 51
1 year 0.00 2.67 [1.33, 5.35] 5.5e-3 10

Correlations

Index endpoint: M13_SPONDYLOLISTHESIS – Spondylolisthesis/Spondylolysis
GWS hits: 1

Survival analyses between endpoints

Plot

before Spondylolisthesis/Spondylolysis
after Spondylolisthesis/Spondylolysis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Spondylolisthesis/Spondylolysis