Pre-eclampsia or eclampsia

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O11, O14, O15.0, O15.1, O15.2
Hospital discharge: ICD-9 642[4-7]
Hospital discharge: ICD-8 6370[349]|63710|63799|66120
Cause of death: ICD-10 O11, O14, O15.0, O15.1, O15.2
Cause of death: ICD-9 642[4-7]
Cause of death: ICD-8 6370[349]|63710|63799|66120

Check pre-conditions None

Include endpoints None

Check conditions None

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Apply sex-specific rule

Sex only females
diagram downward connector O15_PRE_OR_ECLAMPSIA

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 4743 4743 -
Unadjusted prevalence (%) 1.82 3.23 -
Mean age at first event (years) 28.94 28.94 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.62 [0.42, 0.91] 1.5e-2 86
15 years 0.00 0.51 [0.32, 0.80] 3.5e-3 34
5 years - - - -
1 year - - - -


Index endpoint: O15_PRE_OR_ECLAMPSIA – Pre-eclampsia or eclampsia
GWS hits: 0

Survival analyses between endpoints


before Pre-eclampsia or eclampsia
after Pre-eclampsia or eclampsia

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Drugs most likely to be purchased after Pre-eclampsia or eclampsia