Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O10-O16
Hospital discharge: ICD-9 642
Hospital discharge: ICD-8 637
Cause of death: ICD-10 O10-O16
Cause of death: ICD-9 642
Cause of death: ICD-8 637

Check pre-conditions None

Check conditions None

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Apply sex-specific rule

Sex only females
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Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Similar endpoints

List of similar endpoints to Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 10736 10736 -
Unadjusted prevalence (%) 4.13 7.31 -
Mean age at first event (years) 29.30 29.30 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.61 [0.48, 0.78] 5.9e-5 211
15 years 0.00 0.55 [0.42, 0.73] 3.6e-5 92
5 years - - - -
1 year - - - -

Correlations

Index endpoint: O15_OEDEM_PROTUR_HYPERT – Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
GWS hits: 6

Survival analyses between endpoints

Plot

before Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
after Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

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Drugs most likely to be purchased after Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium