Pregnancy hypertension

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

FinnGen phenotype data
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Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O10, O11, O13, O14, O15, O16
Hospital discharge: ICD-9 642
Hospital discharge: ICD-8 63701|63703|63704|63709|63710|63799
Cause of death: ICD-10 O10, O11, O13, O14, O15, O16
Cause of death: ICD-9 642
Cause of death: ICD-8 63701|63703|63704|63709|63710|63799

Check pre-conditions None

Include endpoints None

Check conditions None

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Apply sex-specific rule

Sex only females
diagram downward connector O15_HYPTENSPREG

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Pregnancy hypertension based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 9354 9354 -
Unadjusted prevalence (%) 3.60 6.37 -
Mean age at first event (years) 29.58 29.58 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.78 [0.61, 1.01] 5.6e-2 178
15 years 0.01 0.72 [0.53, 0.96] 2.8e-2 79
5 years - - - -
1 year - - - -


Index endpoint: O15_HYPTENSPREG – Pregnancy hypertension
GWS hits: 8

Survival analyses between endpoints


before Pregnancy hypertension
after Pregnancy hypertension

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Drugs most likely to be purchased after Pregnancy hypertension