Pre-eclampsia

DOID EFO MESH SNOMED PheWeb

preeclampsia: Preeclampsia is a hypertensive disorder of pregnancy that is characterized by new-onset hypertension with proteinuria presenting after 20 weeks of gestation, and depending on mild or severe forms may initially present with severe headache, visual disturbances, and hyperreflexia.

Endpoint definition

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FinnGen phenotype data

Filter registries Inpat., Oupat., Death

Hospital Discharge: ICD-10 O14

Hospital discharge: ICD-9 642[4-5]

Hospital discharge: ICD-8 6370[349]

Cause of death: ICD-10 O14

Cause of death: ICD-9 642[4-5]

Cause of death: ICD-8 6370[349]

Check pre-conditions None

Include endpoints None

Check conditions None

Apply sex-specific rule

Sex only females

O15_PREECLAMPS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF5

Parent code in ICD-10 O10-O16

Name in latin Hypertensio gestationalis cum proteinuria significanti

Similar endpoints

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List of similar endpoints to Pre-eclampsia based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4349	4349	-
Unadjusted prevalence (%)	1.67	2.96	-
Mean age at first event (years)	28.99	28.99	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.69 [0.49, 0.96]	2.7e-2	74
15 years	0.00	0.57 [0.37, 0.88]	1.2e-2	30
5 years	-	-	-	-
1 year	-	-	-	-

Correlations

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Index endpoint: O15_PREECLAMPS – Pre-eclampsia
GWS hits: 0

Survival analyses between endpoints

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Plot

before Pre-eclampsia
after Pre-eclampsia

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Pre-eclampsia

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